Understand the research behind peptides — before you spend a dollar on them.
73 peptides and compounds covered: mechanism, evidence quality, and honest notes on what's actually been studied in humans versus what hasn't.
Cognitive
Nootropic and neuroprotective peptide research, explained in plain language.
Supplies & sourcing
Where researchers source vials, reconstitution supplies, and testing kits.
Browse →Protocol cheat sheets
18 printable reference sheets covering reconstitution and storage research.
Browse →Latest research news
63 tracked articles on trial results and new peptide research as it publishes.
Browse →BPC-157
BPC-157 is a synthetic pentadecapeptide based on a partial sequence of a human gastric juice protective protei…
Growth Hormone (GHRH)CJC-1295
CJC-1295 (without DAC, chemically equivalent to Modified GRF 1-29) is a synthetic analog of the first 29 amino…
HealingGHK-Cu
GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) whose tissue levels dec…
LongevityMOTS-c
MOTS-c is a 16-amino-acid mitochondrial-derived peptide, encoded within the mitochondrial 12S rRNA gene, that …
Weight LossSemaglutide
Semaglutide is an FDA-approved GLP-1 receptor agonist sold as Ozempic and oral Rybelsus for type 2 diabetes an…
Weight LossTirzepatide
Tirzepatide is an FDA-approved dual GIP/GLP-1 receptor agonist marketed as Mounjaro for type 2 diabetes and Ze…
Oral Peptide Icotrokinra Meets Primary Endpoint in First Phase 3 Psoriatic Arthritis Trial
Johnson & Johnson's Phase 3 ICONIC-PsA 1 trial, presented at the 2026 ACR Convergence meeting, is the first look at icotrokinra, an oral peptide that blocks the IL-23 receptor, in people with active psoriatic arthritis who had not yet tried a biologic drug. At 16 weeks, significantly more patients on icotrokinra saw meaningful joint-symptom improvement than on placebo, with even larger gains in skin clearance among those with qualifying psoriasis. Response rates kept climbing through 24 weeks of follow-up, and investigators reported no new safety signals beyond icotrokinra's established profile. The peptide, sold as Icotyde and already FDA-approved for plaque psoriasis, is not yet approved for psoriatic arthritis.
BPC-157: What the Research Actually Shows
A look at the animal data behind the internet's favorite recovery peptide, and the gap between preclinical promise and human evide…
GLP-1, GIP, and Triple Agonists: How the Weight-Loss Peptide Class Actually Works
Semaglutide, tirzepatide, and retatrutide all act on incretin hormone receptors, but each targets a different combination. Here's …
Why CJC-1295 and Ipamorelin Are Almost Always Discussed Together
The pairing shows up constantly in peptide literature because the two compounds act on two different, complementary steps of the s…
TB-500 and Thymosin Beta-4: What the Evidence Actually Covers
TB-500 is often discussed alongside BPC-157 for soft-tissue recovery. A 2026 scoping review shows where that evidence base actuall…
PT-141 (Bremelanotide): The One Peptide in This Category the FDA Actually Approved
Most research peptides never see a completed human trial. PT-141 is the exception — it's an FDA-approved drug called Vyleesi. Here…
Semax: The BDNF Mechanism, and Why the Evidence Base Stops at Russia's Border
Semax has been a prescription drug in Russia since 2011, with a genuine trail of published research behind it. Almost none of that…
How to Read a Research Summary
What “preclinical,” “animal model,” and “no completed human trials” actually mean, and why that distinction matters more than a compound's popularity.
Read more →Reconstitution Math
The arithmetic behind mixing a lyophilized vial to a target concentration — unit conversion only, no amounts recommended.
Read more →Evaluating a Vendor
What third-party testing, COAs, and a vendor's own research-use disclaimers can and can't tell you before you buy.
Read more →Why We Don't Publish Dosing
Every entry on this site stops short of amounts and schedules on purpose — here's the reasoning, and where that information does responsibly live.
Read more →Find a Starting Point
Not sure which compound is relevant to what you're researching? Filter the full directory by category and research status.
Read more →Storage & Handling
How temperature, light, and freeze-thaw cycles affect lyophilized powder versus reconstituted solution, and what shortens shelf life.
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